The potential neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), glial cell-line derived neurotrophic factor (GDNF), and nerve growth factor (NGF), makes them efficient therapeutic candidates for neurodegenerative diseases (121). This evidence concerns the gene CNTF and neurodegenerative disease.