Cheong and colleagues (22) found a positive correlation (r = 0.445, p < 0.001) between serum AST levels and liver inflammatory activities in CHB or CHC patients with ALT ≤ 60 IU/L, and AST yielded the highest performance (AUROC = 0.784) for predicting significant inflammation compared with other clinical variables. Here, GPT is linked to cryohydrocytosis.