Five out of those 13 genes were reported to be associated with hearing loss or intellectual disability, including forkhead box C1 (FOXC1), serpin family B member 6 (SERPINB6), tubulin beta 2A class IIa (TUBB2A), tubulin beta 2B class IIb (TUBB2B) and anscription factor AP-2 alpha (TFAP2A). The gene discussed is FOXC1; the disease is hearing loss disorder.