As shown in Figure 4B, there was a statistically significant negative correlation between RRM2 and four miRNAs in HCC, including miR-125b-5p (r = −0.434, p = 2.12e-18), let-7c-5p (r = −0.36, p = 9.39e-13), miR-30a-5p (r = −0.282, p = 3.60e-8) and let-7g-5p (r = −0.163, p = 1.61e-03). This evidence concerns the gene RRM2 and hepatocellular carcinoma.