BRCA1 and breast carcinoma: In addition, there are other potent targets in BC, such as the B-Raf protein-encoding gene (BRAF), breast cancer genes (BRCA1/2), epidermal growth factor receptor 2 (HER2), anaplastic lymphoma tyrosine kinase receptor (ALK), receptor tyrosine kinase-encoding proto-oncogene (RET), and neurotrophic receptor tyrosine kinase gene (NTRK), which are actively being investigated [4].