COQ10B and neoplasm: In order to investigate COQ10B expression in ESCC, we collected tumor and surrounding tissues from 40 ESCC patients for qRT-PCR detection, and the result revealed the higher expression of COQ10B in ESCC tissues than that in surrounding normal tissues (1.644 ± 0.543 vs. 0.793 ± 0.492, P < 0.05, Figure 1(a)).