Our analysis of the TCGA database shows that YAP1 is highly expressed in esophageal cancer (P=0.498), gastric cancer (P=0.012), cholangiocarcinoma (P=0.018), pancreatic cancer (P=0.018), and colorectal cancer (P < 0.0001) relative to normal tissues. The gene discussed is YAP1; the disease is esophageal cancer.