Several advantages for human health are attributed to chickpea proteins and lupin proteins: the lupin lectin γ-conglutin, a globulin composed of 42 kDa subunits, showed beneficial properties through its reducing effect in glycemia being suitable for diabetics (14, 51); the deflamin protein found in legume seeds, namely lupin and chickpea, has been shown to be anti-inflammatory in in vitro models with various colon cancer cell lines as well as in vivo models of acute and chronic disease, presenting inhibitory bioactivity against MMP-9 (24, 27). Here, NT5C3A is linked to colonic neoplasm.