Following univariate analysis of age, N/L, PCT, CRP, TB, Scr, BNP, Alb, PT, APTT, Lac, SCMM-CD4, SCMM-CD8, and APACHE II score in both groups, multivariate logistic regression analysis was performed on indicators that showed statistical differences to eliminate the interference of confounding factors. The gene discussed is CD4; the disease is tuberculosis.