To clarify whether MUC1 was involved in the occurrence and development of ferroptosis in sepsis ALI, we treated mice with the MUC1 inhibitor GO203 and its control CP2 before CLP modeling and performed western blot and redox product detection 24 h after modeling to explore the effects of MUC1 on ferroptosis in lungs of sepsis mice. Here, MUC1 is linked to Sepsis.