Luo et al. prepared a tumor-targeted oxygen-carrying hybrid protein nanocarrier composed of Hb and albumin, which encapsulated DOX and Ce6 and dissolved a large number of O2 by Hb so as to produce enhanced PDT via strengthening O2 self-supply and ROS generation, thus leading to the effective elimination of tumors 155. This evidence concerns the gene GSTM1 and neoplasm.