We subcutaneously inoculated DCLK1-B OE or wild-type (WT) cells into NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice and observed that DCLK1-B OE cells generated a larger tumor burden than WT cells (Figure S2A-B). The gene discussed is DCLK1; the disease is neoplasm.