FOXO1 can be phosphorylated by GSK-3β and it has been reported that GSK-3β inhibitor 9-ING-41 treatment sensitizes SU-DHL4 and KPUM-UH1 cells to venetoclax 31, which highlights the complex regulation of FOXO1 in DLBCL. The gene discussed is GSK3B; the disease is diffuse large B-cell lymphoma.