To further investigate the function of EGR1 in renal tubule repair after AKI, we constructed Egr1 overexpressing mice by injecting a pPax8-Egr1-CFP plasmid into mice to facilitate kidney tubule-specific Egr1 overexpression (Egr1Pax8-OV-CFP). Here, EGR1 is linked to acute kidney injury.