SPRY1 and glioblastoma: The Ivy Glioblastoma Atlas Project dataset contains mRNA expression profiles of different tumor areas: cellular tumor (CT), infiltrating tumor (IT), leading-edge (LE), microvascular proliferation (MVP), hyperplastic blood vessels (HBV), pseudopalisading cells around necrosis (PAN), and perinecrotic zone (PNZ) and was used to understand the histological importance of SPRY1 (Fig. 5D).