P2RX3 and idiopathic pulmonary fibrosis: Based on therapeutic studies in the chronic non-IPF idiopathic cough population, future study should focus on medications that suppress the cough reflex, such as gabapentin, pregabalin amitriptyline, inhaled cromolyn sodium (PA101), or P2X3 inhibitors, which may provide cough alleviation in IPF as well (50, 62).