In the in vitro study by Biswas et al., TO homeopathic mother tincture was shown to decrease cell viability and proliferation and induce cell death through apoptotic induction in A375 cancer cells by favouring mitochondrial transmembrane collapse, internucleosomal DNA fragmentation, increased ROS generation, and the activation of caspase-3 (Biswas et al., 2011). Here, CASP3 is linked to cancer.