Curcumin also lowered adenine-induced high blood pressure, urinary albumin, the inflammatory cytokines interleukins 1 (IL-1) and 6 (IL-6), tumor necrosis factor α (TNF-α), cystatin C (CST3), and adiponectin (ADIPOQ) (Kumar et al., 2021). This evidence concerns the gene TNF and blood pressure trait.