Attempts were also made to correlate R2* values with expression of HIF-1α: the mean R2* value correlated moderately with the level of HIF-1α in breast invasive ductal carcinoma (Liu et al., 2013), in human glioma (Tóth et al., 2013), but no correlation was found in renal carcinoma (Li et al., 2015). The gene discussed is HIF1A; the disease is central nervous system cancer.