Therefore, in this study, the anticancer properties of the novel fluorine-incorporated gold (I) compounds such as triphenylphosphanegold (I) O-methyl-N-3-fluorophenyl thiocarbamate: Ph3PAu[SC(OMe)=NC6H4F-3] (compound 3F1), Bis (diphenylphosphinoferrocene) di gold I O-methyl-N-(3-fluorophenyl) thiocarbamate): DPPFeAu2[(SC(OMe)=NC6H4F-3)]2 (compound 3F3), and their ligand LH (compound 3FL) synthesized by Yeo and colleagues [12, 13] were evaluated in breast cancer cells. The gene discussed is PLOD1; the disease is breast cancer.