Of the 12 selected variants, we replicated 4 variants in phenotype COVID-19 related pneumonia/without pneumonia (the same as severe and moderate versus mild) (IFNAR2 rs13050728, LZTFL1 rs35081325, CCHCR1 rs143334143, ACE2 rs2106809) and 2 variants in phenotype severe/mild (LZTFL1 rs35081325, CCHCR1 rs143334143) at least at nominal p-value of 0.05 (Supplementary Table S6). The gene discussed is ACE2; the disease is COVID-19.