In this study, we performed whole transcriptome sequencing to identify 117 DElncRNAs as well as 513 differentially expressed mRNAs by extracting serum exosomes from ovarian cancer patients and combining 841 predicted target genes derived from the miRcode database and miRNA target gene prediction website to obtain 11 potential target genes related to ovarian cancer (FGFR3, BMPR1B, TRIM29, FBN2, PAPPA, CCDC58, IGSF3, FBXO10, GPAM, HOXA10, and LHFPL4). This evidence concerns the gene PAPPA and ovarian cancer.