There were a few studies on the prognostic value of ADAMTS2 in GC, but the evidence of its diagnostic value on GC is limited (Jiang et al., 2019; Liang et al., 2020), while previous study showed that high levels of COL10A1 in plasma could provide diagnostic value in GC with AUC of 0.9171 (p = 0.0002) (Necula et al., 2020). This evidence concerns the gene ADAMTS2 and gastric cancer.