ADRA2B and cancer: Autocrine signaling-related genes, such as CACNA1C, COL4A5, ADRA2B, FZD7, IL20RB, PMCH, and EPHB2, were implicated in some types of cancer (Ikeda et al., 2006; Merlos-Suárez et al., 2011; Kiaii et al., 2013; Phan et al., 2017; Zhang et al., 2018; Cui et al., 2019; Ye et al., 2019).