Widespread increases in inflammatory factors like TNF-α, interleukin 8(IL-8), Interleukin 6 (IL-6) (NF)-kB, and CRP levels have been observed in OSA patients and can be alleviated by CPAP treatment (Garvey et al., 2009; Kheirandish-Gozal and Gozal, 2019; Thompson et al., 2022). This evidence concerns the gene TNF and obstructive sleep apnea syndrome.