In the type 2 diabetes CDC123/CAMK1D GWAS (genome-wide association studies) locus, rs11257655 affects transcriptional activity by altering the binding of the protein complexes of FOXA1 and FOXA2, a potential molecular mechanism in type 2 diabetes (Fogarty et al., 2014). This evidence concerns the gene FOXA2 and type 2 diabetes mellitus.