CD274 and mismatch repair cancer syndrome 1: Furthermore, many previous studies have shown that PD-L1 is a notable manifestation in cervical carcinoma (Reddy et al., 2017; Chinn et al., 2019), and some scholars have also confirmed that treatment of immune check-point is working in patients with PD-L1 positive and MMRS deficiency (Ji et al., 2021).