Immunofluorescence staining revealed that NaB remarkably reduced glomerular collagen fibril IV deposition (COV IV) (Figure 2(g)); NaB effectively downregulated TGF-β, Fn, IL-6, and MCP-1 expression in DKD kidney tissues by qRT-PCR (Figures 2(h) and 2(i)); NaB downregulated the protein expression of IL-6 and TGF-β in cells induced by high glucose by Western blotting (Figure 2(j)). Here, CCL2 is linked to diabetic kidney disease.