AKT1 and hepatocellular carcinoma: The expression levels of p-PI3K and p-Akt protein in HuH-7 hepatoma cells in the PI3K activator group significantly increased (P < 0.05), while the expression levels of p-PI3K and p-Akt protein in HuH-7 hepatoma cells in the circFOXO3 mimic group significantly decreased (P < 0.05).