Furthermore, the smallest active snippet of ADNP, an eight-amino-acid peptide NAP (NAPVSIPQ), protected against ADNP deficiencies in autism patients with Helsmoortel-Van Der Aa syndrome (Merenlender-Wagner et al., 2014; Sragovich et al., 2017; Gozes, 2021; Ivashko-Pachima et al., 2021). The gene discussed is ADNP; the disease is ADNP-related multiple congenital anomalies-intellectual disability-autism spectrum disorder.