For example, the sevenfold higher density of PECAM-1-positive capillaries in the cell body-rich area of mouse DRG than in the cell fiber-rich area of the DRG or the sciatic nerve facilitated many potentially neurotoxic agents by preferentially accumulating and injuring cells within the DRG, thereby inducing peripheral sensory neuropathy (Jimenez-Andrade et al., 2008). The gene discussed is PECAM1; the disease is sensory peripheral neuropathy.