AIF1 and Alzheimer disease: However, as the same as in 9‐month‐old APPtgp38fl/flLysM‐Cre+/− mice, p38α‐MAPK deficiency specifically in microglia also promoted the accumulation of Iba‐1‐positive microglia around Aβ deposits in both cortex and hippocampus of 12‐month‐old APPtgp38fl/flCx3Cr1‐Cre+/− mice compared with p38α‐MAPK‐wildtype AD mice (Figure 5p,q).