The previous studies have reported that β-Ele can inhibit cell proliferation, induce cell cycle arrest and enhance cisplatin-induced cell death in human solid tumors, such as bladder cancer, lung cancer through regulation of extracellular signal regulated kinase (ERK) and phosphoinositol 3-kinase (PI3K)/Akt signaling pathways [6, 7]. Here, AKT1 is linked to urinary bladder cancer.