Among these 18 IRDS genes, a subset of 10 STAT1‐driven genes (IFI44, IFI44L, IFI6, IFIT1, IFIT3, IFITM1, MX1, MX2, OAS1 and OAS3) are positively correlated with STAT1 in clinical TCGA PCa dataset (Figure 1E) and elevated in PCa patients with lymph node metastasis (Figure 1F). Here, STAT1 is linked to posterior cortical atrophy.