Indeed, in contrast to STAT1 (Figure 1C and Figure S1C), TP53 level is significantly reduced in PCa patients with higher grade (Figure S1G) or lymph node metastasis (Figure S1H), and inversely correlated with STAT1 level based on TCGA PCa dataset (Figure S1I). Here, STAT1 is linked to metastatic malignant neoplasm in the lymph nodes.