WTAP stabilizes Fak mRNA in PC to promote metastasis and gemcitabine resistance,41 PIK3CB m6A methylation promotes the progression of PTEN‐deficient PC by regulating the AKT signaling pathway,42 but the pattern of methylation and the progression of malignancy in PC remain to be explored. This evidence concerns the gene AKT1 and pachyonychia congenita.