Among the genes to which EHDN mapped CAG repeats in individuals diagnosed with hereditary corneal dystrophies (H185) were genes with non-RE mutations linked to ocular disorders and dystrophies, including AGBL1 (n = 10, causal for FECD type 849), PDK3 (n = 23, Charcot-Marie-Tooth disease, type 6, which involves development of optic atrophy among other symptoms50), POLG (n = 2, progressive external ophthalmoplegia51), and RAB28 (n = 1, previously associated with cone-rod dystrophies52). The gene discussed is POLG; the disease is hereditary optic atrophy.