In the present research, we demonstrated that EBV-miR-BART-22 in NPC cells significantly reduced the expression of E-cadherin, an important epithelial phenotype marker, and increased the expression of the mesenchymal phenotype markers N-cadherin and vimentin (Figs. 4G and 5G). The gene discussed is CDH2; the disease is nasopharyngeal carcinoma.