According to previous studies, there are two central different cell states (epithelial and mesenchymal) in the process of EMT, which is usually characterized by the loss of the epithelial characteristics E-cadherin and α-catenin in cancer cells and the acquisition of the mesenchymal marker vimentin and N-cadherin, as well as imparting tumor cell metastasis [14]. The gene discussed is CDH2; the disease is neoplasm.