IHC staining of tumor sections of xenografts and metastasized organs demonstrated that the upregulation of EBV-miR-BART-22 overtly reduced E-cadherin expression but increased the expression of N-cadherin and vimentin in CNE-1-BART22 tumors compared with the CNE1-mock control tumors (Fig. S5B). This evidence concerns the gene CDH2 and neoplasm.