Of these, only the expression of MOSPD2 was significantly decreased in EBV-negative NPC cells with ectopic expression of EBV-miR-BART-22 versus control cells, whereas it was upregulated in EBV-positive NPC cells with genetic downregulation of EBV-miR-BART-22 (Fig. 7B). The gene discussed is MOSPD2; the disease is nasopharyngeal carcinoma.