CD4 and neoplasm: The clustering of T/NK cells of the tumor environment revealed 5 main populations, including NK/NKT subtype (GNLY and TRDC), γδ T cells (GNLY, TRDC, and CD3D), CD4+CD8+ T cell subtype (CD3D, CD8A, and CD4), CD8+ T cells (CD3D and CD8A), and CD4+ T cells (CD3D and CD4) (Fig. 5a, b).