Conversely, induction of NASH significantly decreased RQs of LATS2 mRNA and RPARP AS-1 LncRNA; the RQ of LATS2 mRNA in 12-week NASH, 9-week NASH, and Broth group animals individually with controls showed a significant decrease (45, 14, and 50-fold, respectively; p < 0.01). Here, PTGDR is linked to metabolic dysfunction-associated steatohepatitis.