PRKAA1 and metabolic dysfunction-associated steatotic liver disease: Compared with HFD, the expression of SREBP1 and Scd1 in VEGFB knockout mouse liver increased more markedly, suggesting that after VEGFB gene suppression, the AMPK/SREBP1/Scd1 pathway will be activated, resulting in lipogenesis and lipid accumulation, and accelerating the formation of NAFLD [61].