CDKN2B and colorectal carcinoma: Interestingly, in two very recent studies, CDKN2B-AS1 have been investigated as a tumor oncogene (upregulated) which regulates cell proliferation and inhibit apoptosis in CRC through sponging miR-28-5p and targeting MAPK inactivator dual-specificity phosphatase 1, respectively [59, 60].