We were not able to identify additional IBD patients with a duplication of the IL2RA locus, but there was one unaffected mother who had an IL2RA duplication [DUP:10:5991252:6557098], which also involved five genes [IL15RA, IL2RA, PFKFB3, PRKCQ, and RBM17]. This evidence concerns the gene PFKFB3 and inflammatory bowel disease.