SPG11 and Cerebral atrophy: The aim of this study was to comprehensively characterize the cognitive and cerebral atrophy phenotype in a well-defined cohort of SPG11 patients in order to (1) describe the neuropsychological profile of SPG11, (2) depict the progressive impairment in specific cognitive tasks, (3) quantify atrophy of different predefined brain regions, and (4) ultimately correlate the neuropsychological with the cerebral phenotype.