LINC00460 and cancer: LINC00460 has been reported to be positively associated with lymph node and distant metastases as well as TNM stage in diverse malignancies, including bladder [59], colorectal [21, 22, 24], esophageal [25], gastric [27], head and neck [39, 41, 42], liver [45] and papillary thyroid [34] cancers, as well as osteosarcoma [49].