Interestingly, compared with their corresponding normal tissues, FBXL7 expression is significantly lower in colon adenocarcinoma, lung adenocarcinoma, lung squamous cell carcinoma, and prostate adenocarcinoma (Fig. 3), implying its potential regulation of Snail1 turnover in these specific cancer tissues. The gene discussed is FBXL7; the disease is prostate adenocarcinoma.