As expected, due to the higher likelihood of patients with proliferative LN to have anti-DNA antibodies, the presence of anti-dsDNA was the most important predictor of kidney disease, followed by the expression of PTPRO gene (the lower its expression, the higher the probability of predicting active LN) and IL10RA gene (the higher its expression, the higher the probability of predicting active LN). The gene discussed is PTPRO; the disease is lobular neoplasia.