We also examined theimmunoreactive density of excitatory synaptic markers (presynaptic marker VGlut2and postsynaptic marker Homer) at the peri-infarct cortex and found increasedimmunoreactivity of both VGlut2 and Homer in ISP-treated stroke mice (Figure S8), but nochanges in ISP-treated naive mice (Figure S8), suggesting thatpost-stroke ISP treatment enhances the post-stroke peri-infarct zone synapsedensity without affecting the stability of synapses in naive non-strokemice. The gene discussed is HOMER1; the disease is Stroke.