It has been known that the infarct area in stroke upregulatesseveral chemokines such as stromal-derived factor 1α (SDF-1α) (Ohab et al., 2006; Robin et al., 2006) and monocyte chemoattractant protein−1 (MCP-1) (Yan et al., 2007) that canattract the migration of neuroblasts through their expression of correspondingreceptors CXR4 and CCR2. Here, CXCL12 is linked to stroke disorder.