Decreased STING expression has been shown to be an independent and adverse predictor of overall survival in human gastric cancer patients.11 Examination of gastric tissue from wild-type mice by immunohistochemistry revealed that levels of Sting expression among H. pylori-infected gastric tissue were significantly reduced compared to uninfected tissues (Figure 5(d)) and, as expected, undetectable in Sting−/− mice (data not shown). This evidence concerns the gene STING1 and gastric cancer.