The genes for epidermal growth factor receptor and anaplastic lymphoma kinase, which have been found to be mutated in human cancers, have also been studied in canine lung adenocarcinoma (Mariotti et al., 2014), and more recently, human epidermal growth factor receptor 2 protein overexpression in immunohistochemistry has also been found in canine lung cancer (Yoshimoto et al., 2020). This evidence concerns the gene ALK and cancer.