After removing Wang et al’s study in rs1982073, heterogeneity of allelic model (C vs T; OR = 1.53; 95% CI = 1.31–1.80; P < .00001 in the fixed-effects model; Fig. 8A) homozygous model (CC vs TT; OR = 2.32; 95% CI = 1.67–3.22; P < .00001 in the fixed-effects model; Fig. 8B), recessive model (CC vs CT+TT; OR = 1.65; 95% CI = 1.26–2.17; P = .0003 in the fixed-effects model; Fig. 8C) was significantly reduced and overturned the previous conclusion, which showed that TGFbeta1 rs1982073 was significantly associated with myopia. The gene discussed is TGFB1; the disease is myopia.